About MEKSI
MEKSI is a proprietary Australian deep technology infrastructure (Patent No. 2016100353) developed to translate decades of research, innovation, and advances in clinical reasoning, evidence-based medicine, cognitive science, and artificial intelligence into real-world healthcare products. The platform continuously evolves by integrating successive generations of artificial intelligence, selecting the technologies best suited to operationalise its patented reasoning framework while preserving an evidence-based approach to clinical reasoning.
Inspired by a growing body of research demonstrating that deficiencies in clinical reasoning contribute significantly to diagnostic error, MEKSI captures, structures, and evaluates the cognitive reasoning process clinicians use during patient consultations. Rather than focusing solely on diagnostic outcomes, it makes visible the reasoning process itself—including clinical data gathering, data interpretation, differential diagnosis generation, evidence-based decision-making, and reflective practice—enabling these skills to be taught, assessed, and continuously improved.
The MEKSI Chatbot is the first customer-facing application built on this infrastructure. Developed for medical students and doctors in training, it provides an evidence-informed learning environment that supports structured clinical reasoning, reflective practice, and evidence-based diagnostic thinking throughout medical education. It is intended solely as an educational tool and is not designed to diagnose patients or replace the clinical judgment of qualified healthcare professionals.
The evidence base
Reducing diagnostic error is increasingly recognised as one of the greatest challenges in improving patient safety. Central to addressing this challenge is the development of robust clinical reasoning.
In his evidence summary, Diagnostic Error: Incidence, Impacts, Causes and Preventive Strategies (2020), Professor Ian Scott highlights that diagnostic error is common, preventable, and frequently results from failures in clinical reasoning rather than deficiencies in medical knowledge alone. He identifies three fundamental domains in which these failures occur—data gathering, data interpretation, and clinical decision-making—and describes how strengthening these domains through structured clinical reasoning, metacognitive reflection, cognitive debiasing, diagnostic checklists, and deliberate reconsideration of diagnoses can improve diagnostic accuracy and patient safety.
This work was further developed by Professor Ian Scott and Associate Professor Carmel Crock in An Organisational Approach to Improving Diagnostic Safety (2023), which argues that improving diagnostic safety requires not only stronger individual clinical reasoning but also educational and organisational systems that promote structured diagnostic processes, reflection, teamwork, communication, and a culture of diagnostic safety.
These principles are reinforced by a substantial body of international research in clinical reasoning, diagnostic safety, cognitive psychology, and medical education. Collectively, this scholarship demonstrates that strengthening clinical reasoning improves diagnostic performance, reduces cognitive error, and contributes to safer patient care.
MEKSI was conceived not as another AI application or OSCE preparation tool, but as an evidence-based clinical reasoning platform built upon contemporary research in diagnostic safety, medical education, and cognitive science. Educational science came first; artificial intelligence is the enabling technology.
MEKSI enables students to engage in realistic, interactive patient encounters specifically designed to strengthen clinical reasoning. Through deliberate practice and personalised formative feedback, learners progressively develop the three domains identified by Professor Scott—data gathering, data interpretation, and clinical decision-making. MEKSI incorporates many of the educational strategies advocated by Scott and Crock, including structured clinical reasoning, metacognitive reflection, cognitive debiasing, diagnostic checklists, deliberate reconsideration of diagnoses, and reflection before diagnostic closure. Rather than simply preparing students to pass examinations, MEKSI develops the reasoning processes that underpin safe clinical practice.
Beyond individual learning, MEKSI introduces a new paradigm for clinical reasoning education. It supports self-directed learning, one-to-one teaching, tutor-facilitated tutorials, small-group teaching, collaborative case discussions, and a true flipped classroom model. Within minutes, educators can create and deliver consistent, evidence-informed, interactive learning experiences to an entire year group, across multiple institutions, or simultaneously to learners around the world. By combining educational quality with unprecedented scalability, MEKSI transforms clinical reasoning education from a resource-intensive activity into a globally deployable learning platform without compromising learner engagement, personalisation, or academic rigour.
Every learner interaction is deliberately structured around the development of clinical reasoning. Consequently, MEKSI complements existing medical curricula by providing unlimited opportunities for deliberate practice, reflection, and formative feedback. Its purpose extends well beyond improving OSCE performance; it is designed to help medical schools develop graduates with stronger clinical reasoning, greater diagnostic accuracy, and the capabilities required to deliver safer, higher-quality patient care.
MEKSI also provides a platform for innovation across the continuum of medical education. Its scalable architecture supports undergraduate and postgraduate education, continuing professional development, interprofessional education, faculty development, and international collaboration. Whether teaching six students in a tutorial or delivering an interactive clinical reasoning programme to thousands of learners across multiple institutions and countries, MEKSI enables educators to deliver consistent, high-quality educational experiences within minutes.
We believe that the future of medical education lies not in teaching students simply what to think, but in helping them learn how to think. By placing evidence-based clinical reasoning at the centre of medical education, MEKSI aims to contribute to a future in which fewer diagnostic errors translate into safer clinicians, safer healthcare systems, and better outcomes for patients.
Meksi is at the forefront of revolutionizing medical education and clinical practice through innovative technology. Our platform combines cutting-edge artificial intelligence with deep medical expertise to create powerful tools that enhance learning, improve patient care, and standardize medical education globally.
Founded by medical professionals who understand the challenges of modern healthcare, Meksi is committed to making high-quality medical education accessible to all, from established institutions to underserved communities worldwide.
Our team brings together expertise in medical practice, education, and technology, working tirelessly to create solutions that make a real difference in healthcare delivery and medical training.

Editorial board
Nothing reaches a learner on the strength of the technology alone. A named board of practising clinicians and academics writes the cases, reviews them for clinical accuracy, and revisits them as guidelines move.

Dr Jawahar Thomas
MBBS FRACGP
Chief Inventor and Founder

Dr Rebecca Saunderson
BMedSci (Hon 1), MBBS (Hon) Mphil, FACD
Editorial Team Member
Professor Dr Craig Adams
MBBS
Editorial Team Member

Dr Norman Eizenberg
Associate Professor
Editorial Team Member